Both are hosted platforms that can run an online store, but they start from different places. Shopify is commerce-first, with native POS, multichannel selling, a large app ecosystem, editable Liquid themes and headless options. Squarespace is design-first, pairing polished templates with built-in commerce, subscriptions, POS, scheduling via Acuity and email campaigns, suited to brands where content and look matter as much as the catalog.
Choose Shopify if…
Choose Shopify if selling is the core of your business and you need deep inventory, multichannel and POS tools, app extensibility or a path to headless commerce.
Choose Squarespace if…
Choose Squarespace if you want a design-led site where content, portfolio or scheduling sits alongside a store, and you prefer an all-in-one tool with fewer moving parts.
- Shopify supports theme code editing in Liquid plus the Hydrogen headless toolkit
- Squarespace bundles appointment scheduling through Acuity Scheduling
- Both offer in-person selling: Shopify POS and a Squarespace POS iOS app